It's been three years since Mike Lane's (Channing Tatum) retirement from stripping, but the former dancer misses the excitement and feeling of being on stage. Most of all, though, he misses the best friends that he ever had, the crew known as the Kings of Tampa. Opportunity comes knocking when the guys look him up as they travel to Myrtle Beach, S.C., for a stripper convention. With the promise of outrageous fun, a reinvigorated Mike can't resist the chance to join in and take it off again.